However, this is different to transgender testosterone therapy in which patients are not deficient in testosterone, but rather receiving supplementation to raise levels to that seen in biological males. HDL was the only lipid parameter that showed a statistically significant increase, with an increase at Visit 1 and a statistically non-significant trend to a further increase at Visit 2. The number of persons seeking treatment has increased substantially in recent years. The N was too small to compare results between different routes of administration. The population in our study is relatively young, and the risks may different in older subjects on hormone therapy. However, the literature on lipid profile changes after estrogen treatment for transgender women has some discrepancies. Performance of a mastectomy for gender reassignment does not involve a nipple reconstruction as defined by CPT code The content is solely the responsibility of the authors and does not necessarily represent the official views of the NIH.
One retrospective study compared transgender and cisgender lipid profiles. Our experience indicates that metabolic changes are minimal and transgender hormone therapy appears to be safe. The study does not have sufficient power to compare the incidence of adverse effects to the general population. The population in our study is relatively young, and the risks may different in older subjects on hormone therapy. Mastectomy for female to male gender reassignment surgery, however, involves mastectomy without restoration of the breast. Estrogen therapy in postmenopausal cisgender women does not affect blood pressure or BMI [ 5 ]. When the work required to provide a service is substantially greater than typically required, it may be identified by adding modifier 22 to the usual procedure code. Despite the association of estrogen use and triglyceride elevations, triglycerides did not change from Baseline to Visit 2. While these changes reflect a shift toward the average cisgender male hemogram parameters, these changes are still within normal human range. While there was a statistically significant difference between cisgender men and cisgender women, transgender women HDL levels were found to lie intermediate to the cisgender averages, not significantly deviating from either [ 6 ]. Data on demographics, clinical response to treatment, and psychosocial status were collected on all transgender persons receiving cross-sex hormone therapy since at the endocrinology clinic at Albany Medical Center, a tertiary care referral center serving upstate New York. Note on Nipple Reconstruction: Spack stated that GD is poorly understood from both mechanistic and clinical standpoints. The N was too small to compare results between different routes of administration. As this was a retrospective chart review, data is limited to what was available, which varied by patient and provider. MtF Table 3 Standard practice in the clinic includes assessment of physical and laboratory parameters at baseline and in follow up visits. There was no change in serum calcium. Neither our study nor Meyer, et al. The number of persons seeking treatment has increased substantially in recent years. Our study also observed an increase in the hemogram parameters for the FtM cohort at Visit 1 and Visit 2. Testosterone use in hormone therapy for transgender men is associated with an increase in hemoglobin and hematocrit [ 11 ], [ 12 ], [ 13 ] [ 14 ], [ 15 ]. While a cross-sectional study did show that a significant proportion The only significant change observed from the lipid profile was an increase in HDL in the MtF cohort, with no significant negative changes — including no significant change in triglycerides — in either cohort. However, the literature on lipid profile changes after estrogen treatment for transgender women has some discrepancies. There was a trend toward decreased blood pressure from baseline to Visit 2, but this did not reach statistical significance. Several trends were observed from the lipid profile with a tendency towards a decrease in HDL, increase in LDL, and decrease in triglycerides; however, none of these changes reached statistical significance. Gender reassignment remains the treatment of choice for strong and persistent gender dysphoria in both categories, but more research is needed on the short-term and long-term effects of puberty-suppressing medications and cross-sex hormones on brain and behavior.
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Transgender Experiences in Therapy - Gender Identity Counseling
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