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Results The mean age of the KOA patients was Angiogenesis is a multistage process resulting in the growth of blood vessels. These findings indicate that bFGF levels may be a monitor of disease severity and could play an essential part in the pathophysiology of degenerative process in OA. The therapy included 10 sessions of 90 minutes each, one session a day. All scored results varied within the range of standard values as described in the current literature. KOA severity was determined using X-ray evaluated according to the Kellgren—Lawrence KL grading and all underwent sonographic examination. Conclusions Plasma bFGF levels were significantly increased in OA patients, and these elevated levels were significantly correlated with the degree of radiographic severity evaluated by KL grading scale and cartilage degeneration evaluated by ultrasound.

Bfgf sex


Serological levels of bFGF and VEGF were assessed by enzyme-linked immunosorbent assays performed according to the manufacturer's instructions on day 1, 2, 5 and 10 of HBO therapy and were compared to mean values of the control group, related to the patient's age and sex, and their development observed over the ten days of HBO. The therapy included 10 sessions of 90 minutes each, one session a day. These findings indicate that bFGF levels may be a monitor of disease severity and could play an essential part in the pathophysiology of degenerative process in OA. Open Access funded by Egyptian Society for Joint Diseases and Arthritis Under a Creative Commons license Abstract Aim of the work The aim of this study was to investigate plasma basic fibroblast growth factor bFGF levels in patients with primary knee osteoarthritis KOA and to correlate it with physical performance, functional status and radiological severity. KOA was bilateral in Previous article in issue. KOA severity was determined using X-ray evaluated according to the Kellgren—Lawrence KL grading and all underwent sonographic examination. This complex chain of procedures is orchestrated by different cytokines and growth factors. Forty-three patients suffering from sudden sensorineural hearing loss or tinnitus were treated with HBO. Conclusions Plasma bFGF levels were significantly increased in OA patients, and these elevated levels were significantly correlated with the degree of radiographic severity evaluated by KL grading scale and cartilage degeneration evaluated by ultrasound. Additional application of exogenous growth factors in conjunction with HBO was not obviously linked by a coherent cause-and-effect chain as far as wound healing is concerned. Crucial mediators of angiogenesis are basic fibroblast growth factor bFGF and vascular endothelial growth factor VEGF ; their in-vivo function is still not fully understood. Results The mean age of the KOA patients was It combines hyperoxic effects with the stimulating potential of post-therapeutic reactive hypoxia. Women showed significantly higher levels of VEGF. As its crucial effects, stimulation of fibroblast growth, induction of collagen synthesis and the initiation of angiogenesis are discussed. All scored results varied within the range of standard values as described in the current literature. Hyperbaric oxygen HBO therapy is an effective adjunct treatment for ischemic disorders such as chronic infection or chronic wounds. Angiogenesis is a multistage process resulting in the growth of blood vessels. In the present data, there was no connection between the VEGF concentration and the patients' ages. It includes degradation of extracellular matrix, proliferation and migration of different cell populations and finally formation of new vessel structures. Patients and methods Sixty patients with primary KOA and 30 healthy individuals were recruited into this study.

Bfgf sex

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  1. This complex chain of procedures is orchestrated by different cytokines and growth factors. Conclusions Plasma bFGF levels were significantly increased in OA patients, and these elevated levels were significantly correlated with the degree of radiographic severity evaluated by KL grading scale and cartilage degeneration evaluated by ultrasound.

  2. Open Access funded by Egyptian Society for Joint Diseases and Arthritis Under a Creative Commons license Abstract Aim of the work The aim of this study was to investigate plasma basic fibroblast growth factor bFGF levels in patients with primary knee osteoarthritis KOA and to correlate it with physical performance, functional status and radiological severity.

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